KPV

KPV is a tripeptide — just three amino acids — derived from the C-terminal of alpha-melanocyte stimulating hormone. Despite its small size, it has earned a substantial place in the anti-inflammatory peptide research literature, particularly in skin and gastrointestinal applications.

What makes KPV unusual is that it appears to dampen inflammation without suppressing the broader immune response — a quality that researchers studying women’s inflammatory conditions, from skin reactivity to gut sensitivity, have found particularly relevant.

Published research has documented KPV’s role in modulating inflammatory cytokines, supporting skin barrier function, and reducing markers of inflammation in gastrointestinal research models. Its small size and targeted action make it one of the cleaner anti-inflammatory tools in the peptide literature.