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Research Peptide

GLP-3 RT

Lean & Sculpt Support

A triple-agonist peptide studied for its action across three metabolic pathways simultaneously. GLP-3 RT represents the next generation of multi-receptor research in metabolic and body composition science.

4.9 (203 Reviews)
For research use only. Not for human consumption.
About the Peptide

Three pathways, one peptide.

GLP-3 RT, known in the research literature as retatrutide, is a synthetic peptide that activates three distinct receptors simultaneously: GLP-1, GIP, and glucagon. It is among the newest entries in the metabolic peptide family and one of the most-discussed compounds in current weight and body composition research.

Most metabolic research focuses on one pathway at a time. GLP-3 RT was designed to engage three at once — a multi-receptor approach that has produced some of the most striking results in metabolic peptide trials to date, particularly relevant to research on the metabolic shifts women experience through midlife and beyond.

Published research has documented retatrutide’s effects on appetite signaling, energy expenditure, and lipid metabolism — with results in clinical trials that have placed it at the center of next-generation metabolic peptide research.

Research Applications

The next generation of metabolic research.

Women’s metabolic health rarely sits in one lane. Retatrutide’s multi-receptor approach reflects how researchers are increasingly thinking about metabolic complexity.

Body Composition


Clinical research on retatrutide has documented some of the most significant changes in body composition observed in any peptide trial to date, with effects on both fat mass and lean tissue.

Appetite & Satiety


By engaging GLP-1 and GIP receptors, retatrutide has been studied for its effects on appetite regulation and the hormonal signals that govern hunger and fullness.

Energy Metabolism


The added glucagon receptor activity distinguishes retatrutide from earlier peptides in the class, with research focused on its effects on resting energy expenditure and lipid metabolism.
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Research Use Only

All products sold by Next Self Labs are intended strictly for laboratory and research use. They are not for human consumption, therapeutic use, cosmetic application, or in-vivo diagnostic use. Products have not been evaluated or approved by the U.S. Food and Drug Administration. By purchasing, you confirm that you are a qualified researcher over the age of 21 and agree to use products solely in accordance with applicable laws.