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Research Peptide

GHK-Cu

4.9 (169 Reviews)
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A copper-bound tripeptide central to anti-aging and skin-repair research. GHK-Cu is one of the most extensively studied peptides for collagen synthesis, tissue remodeling, and regenerative response.

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For RESEARCH USE ONLY (RUO).
About the Peptide

Fifty years of research.

In 1973, researcher Loren Pickart isolated a tripeptide from human plasma that appeared to make aged liver tissue behave like younger tissue. That tripeptide, glycyl-L-histidyl-L-lysine, bound to copper, became GHK-Cu. Fifty years and thousands of studies later, it remains one of the most thoroughly characterized peptides in regenerative science.

Plasma levels of GHK average around 200 ng/mL at age 20. By age 60, that number drops to roughly 80 ng/mL — a decline that parallels the measurable drop-offs in skin repair and regenerative capacity that come with age.

Published research has documented GHK-Cu’s role in stimulating collagen and elastin synthesis, modulating gene expression across thousands of pathways, reducing markers of oxidative stress, and supporting the cellular mechanisms behind wound healing and tissue remodeling. It is, by most measures, one of the most extensively studied peptides in the anti-aging literature.

Research Applications

Peptide science, intentionally tailored for women.

Peptide research has historically been male focused. NextSelf simplifies the science with protocols designed specifically for women, eliminating confusion and supporting real, lasting results for health, skin, and longevity.

Radiant Complexion


Clinical Studies show improvements in skin density and appearance of the fine lines with consistent use, supporting a smoother, more radiant complexion.

Clinically Studied in Women


A 12-week application study in women reported visible improvements in skin density and wrinkle appearance compared to placebo and control groups, highlighting the targeted benefits in peptide based support.

Collagen Support


In comparative studies, GHK-Cu has been shown to support collagen production, with strong results observed in women compared to traditional skin care ingredients like vitamin C and retinoic acid, helping to promote firmer, more youthful looking skin.
How to read a peptide Vial
Certificate of Analysis

Independently Tested. Verified by Batch.

Current Batch  • GHK50MGA
99.86%
Purity
Tested Purity by HPLC
50mg
Content

Labeled amount per vial

53.95mg
Net Content
Actual amount per vial
GHK-CU
Identification
Mass spectrometry confirmed
View COA
Frequently Asked

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