ARA-290
A non-erythropoietic peptide derived from erythropoietin, studied for its role in tissue protection and inflammation. ARA-290 is researched for its effects on neuropathic pain, nerve repair, and the innate repair response.
The copper peptide for hair.
ARA-290 (also called cibinetide) is an 11-amino-acid peptide derived from a specific region of erythropoietin (EPO), the hormone best known for stimulating red blood cell production. What makes ARA-290 distinct is that it was engineered to keep EPO’s tissue-protective signaling while removing its blood-cell-stimulating activity—isolating the repair side of the molecule from the effects that limit EPO’s broader use.
Chronic pain and nerve dysfunction are among the hardest problems women bring to research, in part because so much of it is inflammatory and self-perpetuating. Damaged nerves signal distress, inflammation follows, and the cycle feeds itself. ARA-290 research targets that loop directly at the receptor level.
Published research has documented ARA-290’s role in activating the innate repair receptor (a complex of the EPO receptor and the beta-common receptor), reducing neuropathic pain and supporting small-fiber nerve regeneration, and modulating inflammatory pathways without affecting hematocrit. It has been studied in clinical trials for conditions including sarcoidosis-related neuropathy and diabetic neuropathic pain.
