How should SS-31 be stored?

In lyophilized powder form, SS-31 is stable at room temperature short-term but should be refrigerated (2–8°C) for longer storage and kept away from light and moisture. Once reconstituted, keep refrigerated and use within 30 days. Avoid freeze-thaw cycles.

Is SS-31 approved by the FDA?

No. SS-31 is not FDA-approved for human use. NextSelf Labs sells SS-31 strictly as a research chemical for laboratory research.

What is the purity of your SS-31?

All NextSelf Labs SS-31 is manufactured to ≥99% purity and verified by third-party laboratories using HPLC and mass spectrometry. The Certificate of Analysis for every batch is available on this page — match the batch number on your vial to the COA header to verify.

Why does SS-31 specifically target mitochondria?

SS-31’s structure — alternating cationic and aromatic amino acids — gives it a strong affinity for cardiolipin, a phospholipid found almost exclusively in the inner mitochondrial membrane. That binding is what concentrates the peptide there at thousands of times the cellular average.

Is SS-31 in clinical trials?

Yes. SS-31 (elamipretide) has been in active clinical trials for several mitochondrial-related conditions, including primary mitochondrial myopathy, age-related macular degeneration, and heart failure. NextSelf Labs sells it strictly as a research chemical.

Do I need a prescription to purchase SS-31?

No. NextSelf Labs sells SS-31 as a research chemical for laboratory use only.

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SS-31

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Research Tetrapeptide

SS-31

Energy Restoration Peptide

A mitochondria-targeted tetrapeptide studied for its role in cellular energy and oxidative stress research. SS-31 is one of the most active areas of clinical mitochondrial peptide investigation.

4.9 (74 Reviews)

For research use only. Not for human consumption.

About the Peptide

A peptide that goes deep.

SS-31 (also known as elamipretide) is a synthetic four-amino-acid peptide that selectively concentrates in mitochondria — the cell’s energy organelles — by binding to cardiolipin in the inner mitochondrial membrane. It is one of the most thoroughly characterized mitochondria-targeted peptides in current clinical research.

Mitochondrial dysfunction sits beneath nearly every conversation about aging, energy, and metabolic health. For women, the cumulative effect of mitochondrial decline shows up as fatigue that doesn’t resolve with sleep, exercise capacity that diminishes faster than expected, and the metabolic shifts of midlife.

Published research has documented SS-31’s role in stabilizing mitochondrial cristae structure, improving ATP production, reducing oxidative stress, and restoring mitochondrial function in models ranging from cardiac health to age-related muscle decline. SS-31 is currently in clinical trials for several mitochondrial-related conditions.

Research Applications

When fatigue is mitochondrial.

Some forms of fatigue in women trace back to the cellular energy machinery itself. SS-31 is the peptide research community’s most-studied tool for that conversation.

Mitochondrial Function

SS-31 binds cardiolipin in the inner mitochondrial membrane, stabilizing cristae structure and improving the efficiency of the electron transport chain — the cellular machinery that produces ATP.

Oxidative Stress

Research has documented SS-31’s role in reducing reactive oxygen species production at the source, in mitochondria, where most cellular oxidative stress originates.

Cellular Energy

By improving mitochondrial efficiency, SS-31 has been studied for downstream effects on energy availability, exercise capacity, and the cellular markers of metabolic health.

Certificate of Analysis

Independently Tested. Verified by Batch.

Current Batch • %

Coming Soon

Purity

Tested Purity by HPLC

mg

Content

Labeled amount per vial

mg

Net Content

Actual amount per vial

Identification

Mass spectrometry confirmed

View COA

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Research Use Only

All products sold by Next Self Labs are intended strictly for laboratory and research use. They are not for human consumption, therapeutic use, cosmetic application, or in-vivo diagnostic use. Products have not been evaluated or approved by the U.S. Food and Drug Administration. By purchasing, you confirm that you are a qualified researcher over the age of 21 and agree to use products solely in accordance with applicable laws.

SS-31

A peptide that goes deep.

When fatigue is mitochondrial.

Mitochondrial Function

Oxidative Stress

Cellular Energy

Independently Tested. Verified by Batch.

Questions.

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