How should MT-1 be stored?

In lyophilized powder form, MT-1 is stable at room temperature short-term but should be refrigerated (2–8°C) for longer storage and kept away from light and moisture. Once reconstituted, keep refrigerated and use within 30 days. Avoid freeze-thaw cycles.

Is MT-1 approved by the FDA?

No. MT-1 is not FDA-approved for human use. NextSelf Labs sells MT-1 strictly as a research chemical for laboratory research.

What is the purity of your MT-1?

All NextSelf Labs MT-1 is manufactured to ≥99% purity and verified by third-party laboratories using HPLC and mass spectrometry. The Certificate of Analysis for every batch is available on this page — match the batch number on your vial to the COA header to verify.

What’s the difference between MT-1 and MT-2?

MT-1 (afamelanotide) is more selective for melanin pathway receptors. MT-2 has a broader receptor profile that includes effects on libido and appetite. For pigmentation-focused research, MT-1 is the cleaner tool.

Is afamelanotide approved anywhere?

Afamelanotide has been approved in several countries for the treatment of erythropoietic protoporphyria — a rare condition involving severe photosensitivity. It is not FDA-approved for general use, and NextSelf Labs sells it strictly as a research chemical.

Do I need a prescription to purchase MT-1?

No. NextSelf Labs sells MT-1 as a research chemical for laboratory use only.

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MT-1

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Research Peptide

MT-1

Tanning Support

A synthetic analog of alpha-MSH studied for its role in melanin pathway research. Melanotan I is one of the most-targeted peptides in skin pigmentation and photoprotection studies.

4.9 (64 Reviews)

For research use only. Not for human consumption.

About the Peptide

The more selective melanin signal.

Melanotan I (MT-1), also known as afamelanotide, is a synthetic analog of alpha-melanocyte stimulating hormone (alpha-MSH) — the hormone that signals the body’s pigment-producing cells to make melanin. It is the more selective of the two melanotans in the research literature, with a narrower mechanism focused specifically on the melanin pathway.

For women researchers exploring skin pigmentation, photoprotection, or conditions where melanin signaling matters — from photosensitivity research to studies on uneven complexion — MT-1 has become the more refined of the available tools.

Published research has documented MT-1’s role in stimulating eumelanin production, supporting research into UV-protective pigmentation, and exploring the melanin pathway’s broader connections to skin health.

Research Applications

Melanin pathway research, refined.

Skin pigmentation research has come a long way from the broad strokes of earlier decades. MT-1’s narrower mechanism is part of why.

Pigmentation Pathway

MT-1 has been studied extensively for its role in eumelanin synthesis — the pigment associated with photoprotective skin response and uniformity of tone.

Photoprotection Research

Studies have documented MT-1’s role in supporting research populations exploring UV protection through endogenous pigmentation — a mechanism distinct from topical sunscreen approaches.

Selective Mechanism

Compared to MT-2, MT-1 has a narrower receptor profile, making it the cleaner research tool for studies focused specifically on melanin pathways without confounding signaling.

Certificate of Analysis

Independently Tested. Verified by Batch.

Current Batch • %

Coming Soon

Purity

Tested Purity by HPLC

mg

Content

Labeled amount per vial

mg

Net Content

Actual amount per vial

Identification

Mass spectrometry confirmed

View COA

Frequently Asked

Questions.

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Research Use Only

All products sold by Next Self Labs are intended strictly for laboratory and research use. They are not for human consumption, therapeutic use, cosmetic application, or in-vivo diagnostic use. Products have not been evaluated or approved by the U.S. Food and Drug Administration. By purchasing, you confirm that you are a qualified researcher over the age of 21 and agree to use products solely in accordance with applicable laws.

MT-1

The more selective melanin signal.

Melanin pathway research, refined.

Pigmentation Pathway

Photoprotection Research

Selective Mechanism

Independently Tested. Verified by Batch.

Questions.

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